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Journal of Clinical Microbiology, April 2005, p. 1998-2001, Vol. 43, No. 4
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.4.1998-2001.2004
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Fusarium verticillioides Abscess of the Nasal Septum in an Immunosuppressed Child: Case Report and Identification of the Morphologically Atypical Fungal Strain

Division of Pediatric Hematology/Oncology,¹ Institute of Hygiene, Medical University, Graz ,² Institute of Hygiene and Social Medicine, Medical University, Innsbruck, Austria ,⁴ Centraalbureau voor Schimmelcultures (CBS), Utrecht, The Netherlands³

Received 19 July 2004/ Returned for modification 30 August 2004/ Accepted 18 September 2004

Morphologically atypical Fusarium verticillioides causing a nasal abscess in a severely immunosuppressed child was successfully treated with repeated surgical intervention and liposomal amphotericin B, despite amphotericin B resistance in vitro. Definitive identification was achieved by sequencing the translation elongation factor gene after ribosomal sequencing proved inadequate.

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