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Journal of Clinical Microbiology, May 2005, p. 2452-2455, Vol. 43, No. 5
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.5.2452-2455.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Prevalence of Derepressed AmpC Mutants and Extended-Spectrum ß-Lactamase Producers among Clinical Isolates of Citrobacter freundii, Enterobacter spp., and Serratia marcescens in Korea: Dissemination of CTX-M-3, TEM-52, and SHV-12

Jungmin Kim* and Yu-Mi Lim

Department of Microbiology, Dankook University College of Medicine, Cheonan, Republic of Korea

Received 31 August 2004/ Returned for modification 25 October 2004/ Accepted 29 December 2004

The resistance mechanism of extended-spectrum cephalosporins in clinical isolates of Citrobacter freundii, Enterobacter spp., and Serratia marcescens was studied. Of 152 isolates, 45 isolates (29.6%) were derepressed AmpC mutants and 39 isolates (25.7%) produced extended-spectrum ß-lactamase (ESBLs). The most prevalent ESBLs were CTX-M enzymes, followed by TEM-52 and SHV-12.

* Corresponding author. Present address: Department of Microbiology, Kyungpook University School of Medicine, Daegu, Korea. Phone: 82-53-420-4845. Fax: 82-53-427-5664. E-mail: minkim{at}dankook.ac.kr.

Journal of Clinical Microbiology, May 2005, p. 2452-2455, Vol. 43, No. 5
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.5.2452-2455.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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