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Journal of Clinical Microbiology, May 2005, p. 2481-2484, Vol. 43, No. 5
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.5.2481-2484.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Identification and Characterization of Genomic Variations between Mycobacterium bovis and M. tuberculosis H37Rv

Ariel Amadio,1 María Isabel Romano,2 Fabiana Bigi,2 Ignacio Etchechoury,2 Tanja Kubica,3 Stefan Niemann,3 Angel Cataldi,2* and Karina Caimi2

Institute of Microbiology and Agricultural Zoology,1 Institute of Biotechnology, CICVyA-INTA, Castelar, Argentina,2 Forschungszentrum Borstel, National Reference Center for Mycobacteria, D-23845 Borstel, Germany3

Received 18 June 2004/ Returned for modification 9 August 2004/ Accepted 17 January 2005

Genetic differences between Mycobacterium bovis and M. tuberculosis were identified. We found (i) a deletion of Rv3479 specific to M. bovis, (ii) that the rpfA gene is shortened to various extents in M. bovis, and (iii) an insertion in Rv0648 and a duplication of lppA common in M. tuberculosis complex isolates.

* Corresponding author. Mailing address: Instituto de Biotecnología, CICVyA/INTA, Los Reseros y Las Cabañas, 1712 Castelar, Argentina. Phone: 54-11-4621-1447. Fax: 54-11-4621-0199. E-mail: acataldi{at}cnia.inta.gov.ar.

Journal of Clinical Microbiology, May 2005, p. 2481-2484, Vol. 43, No. 5
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.5.2481-2484.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

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