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Journal of Clinical Microbiology, June 2005, p. 2913-2915, Vol. 43, No. 6
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.6.2913-2915.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Clinical Relevance of the vacA, iceA, cagA, and flaA Genes of Helicobacter pylori Strains Isolated in Eastern Taiwan

Chao-Chuan Wu,1 Pai-Yu Chou,1 Chi-Tan Hu,2 Zuo-Chai Liu,2 Chih-Yung Lin,2 Yi-Hsiung Tseng,3 and Nien-Tsung Lin4*

Department of Surgery, Tzu Chi General Hospital, Hualien 970, Taiwan,1 Division of Gastroenterology, Tzu Chi General Hospital, Hualien 970, Taiwan,2 Center for Research and Development, Chungtai Institute of Health Sciences and Technology, Taichung 406, Taiwan,3 Department of Microbiology, Tzu Chi University, Hualien 970, Taiwan4

Received 22 January 2005/ Accepted 3 February 2005

The genotypes of Helicobacter pylori flaA, cagA, vacA, and iceA were determined for DNA isolated from patients with chronic gastritis or peptic ulcer in eastern Taiwan. The vacA gene encoding the s1a subtype was found to predominate in peptic ulcer patients, and the iceA1 genotype was associated with chronic gastritis. cagA and flaA genes were not found to be associated with these types of disease.

* Corresponding author. Mailing address: Department of Microbiology, Tzu Chi University, Hualien 970, Taiwan. Phone: 886-3-8565301, ext. 7195. Fax: 886-3-8566724. E-mail: ntlin{at}mail.tcu.edu.tw.

Journal of Clinical Microbiology, June 2005, p. 2913-2915, Vol. 43, No. 6
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.6.2913-2915.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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