This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kerényi, M. Articles by Pál, T. Search for Related Content PubMed PubMed Citation Articles by Kerényi, M. Articles by Pál, T.

Occurrence of hlyA and sheA Genes in Extraintestinal Escherichia coli Strains

Departments of Medical Microbiology and Immunology,¹ Anesthesiology and Intensive Therapy, Medical School, University of Pécs, Hungary,³ School of Biological Sciences, Division of Microbiology and Genomics, University of Liverpool, Liverpool, United Kingdom,² Department of Medical Microbiology, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al-Ain 17666, United Arab Emirates⁴

Received 10 August 2004/ Returned for modification 3 September 2004/ Accepted 3 February 2005

The association of a hemolytic phenotype with the carriage of the -hemolysin gene (hlyA) and/or the silent hemolysin gene (sheA or clyA) among 540 extraintestinal clinical isolates of Escherichia coli and 110 fecal isolates from healthy individuals was investigated. Though HlyA is an important virulence factor in extraintestinal E. coli infection, the role of SheA is not completely clarified. Two hemolytic sheA⁺ E. coli strains that lacked hlyA and possessed no other hemolysin genes were identified. No hlyA⁺ sheA⁺ strains were identified, suggesting that there is possible incompatibility between hlyA and sheA in the chromosome of E. coli.

This article has been cited by other articles:

• Hunt, S., Moir, A. J. G., Tzokov, S., Bullough, P. A., Artymiuk, P. J., Green, J. (2008). The formation and structure of Escherichia coli K-12 haemolysin E pores. Microbiology 154: 633-642 [Abstract] [Full Text]  
• Muller, D., Greune, L., Heusipp, G., Karch, H., Fruth, A., Tschape, H., Schmidt, M. A. (2007). Identification of Unconventional Intestinal Pathogenic Escherichia coli Isolates Expressing Intermediate Virulence Factor Profiles by Using a Novel Single-Step Multiplex PCR. Appl. Environ. Microbiol. 73: 3380-3390 [Abstract] [Full Text]  
• Muller, C. M., Dobrindt, U., Nagy, G., Emody, L., Uhlin, B. E., Hacker, J. (2006). Role of Histone-Like Proteins H-NS and StpA in Expression of Virulence Determinants of Uropathogenic Escherichia coli.. J. Bacteriol. 188: 5428-5438 [Abstract] [Full Text]