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Journal of Clinical Microbiology, June 2005, p. 2973-2975, Vol. 43, No. 6
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.6.2973-2975.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Molecular Diagnosis of Lymphogranuloma Venereum in Patients with Genital Ulcer Disease

Patrick D. J. Sturm, Prashini Moodley, Keshnie Govender, Louise Bohlken, Trusha Vanmali, and A. Willem Sturm*

Genital Ulcer Disease Research Unit of the University of KwaZuluNatal and the South African Medical Research Council, Department of Medical Microbiology, University of KwaZuluNatal, Durban, South Africa

Received 9 August 2004/ Returned for modification 16 December 2004/ Accepted 29 January 2005

The detection of herpes, chancroid, and syphilis in genital ulcers is done by PCR. This is not so for lymphogranuloma venereum (LGV). We report on the use of a PCR with digestion that differentiates the LGV biovar from the trachoma biovar. Our findings suggest that the clinical description of LGV in current textbooks is incomplete.

* Corresponding author. Mailing address: Department of Medical Microbiology, Nelson R. Mandela School of Medicine, Private Bag 7, Congella 4013, South Africa. Phone: 27-31-2604395. Fax: 27-31-2604431. E-mail: sturm{at}kznu.ac.za.

Journal of Clinical Microbiology, June 2005, p. 2973-2975, Vol. 43, No. 6
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.6.2973-2975.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Chen, C-Y, Chi, K H, Alexander, S, Ison, C A, Ballard, R C (2008). A real-time quadriplex PCR assay for the diagnosis of rectal lymphogranuloma venereum and non-lymphogranuloma venereum Chlamydia trachomatis infections. Sex. Transm. Infect. 84: 273-276 [Abstract] [Full Text]  
  • Herring, A, Richens, J (2006). Lymphogranuloma venereum. Sex. Transm. Infect. 82: iv23-iv25 [Full Text]  
  • Klint, M., Lofdahl, M., Ek, C., Airell, A., Berglund, T., Herrmann, B. (2006). Lymphogranuloma Venereum Prevalence in Sweden among Men Who Have Sex with Men and Characterization of Chlamydia trachomatis ompA Genotypes. J. Clin. Microbiol. 44: 4066-4071 [Abstract] [Full Text]  
  • Morre, S. A., Spaargaren, J., Fennema, J. S. A., de Vries, H. J. C., Sturm, P. D. J., Moodley, P., Govender, K., Bohlken, L., Vanmali, T., Sturm, A. W. (2005). Molecular Diagnosis of Lymphogranuloma Venereum: PCR-Based Restriction Fragment Length Polymorphism and Real-Time PCR. J. Clin. Microbiol. 43: 5412-5413 [Full Text]  


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