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Journal of Clinical Microbiology, July 2005, p. 3512-3515, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3512-3515.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

First Infection with VanD-Type Glycopeptide-Resistant Enterococcus faecium in Europe

Jean-Philippe Lavigne,1,2 Hélène Marchandin,1,3 Nicole Bouziges,1,2 and Albert Sotto1,4*

Laboratoire Universitaire d'Antibiologie, Faculté de Médecine, Avenue Kennedy, 30900 Nîmes, France,1 Laboratoire de Bactériologie, Virologie, Parasitologie, CHU de Nîmes, Groupe Hospitalo-Universitaire de Carémeau, Place du Professeur Robert Debré, 30029 Nîmes Cedex 9, France,2 Laboratoire de Bactériologie, CHU Arnaud de Villeneuve, 371, avenue du Doyen Gaston Giraud, 34295 Montpellier cedex 5, France,3 Service de Médecine Interne B, CHU de Nîmes, Groupe Hospitalo-Universitaire de Carémeau, Place du Professeur Robert Debré, 30029 Nîmes Cedex 9, France4

Received 14 January 2005/ Returned for modification 28 February 2005/ Accepted 28 March 2005

We report the first strain of glycopeptide-resistant Enterococcus faecium from Europe that contains a vanD allele isolated from blood cultures of an immunocompromised patient hospitalized in a French university hospital. Based on phenotypic results, PCR sequencing, pulsed-field gel electrophoresis, and Southern blotting, the isolate was assigned to E. faecium with a chromosomally located VanD allele most closely related to the VanD1 allele.

* Corresponding author. Mailing address: Laboratoire Universitaire d'Antibiologie, Faculté de Médecine, CS83021, Avenue Kennedy, 30908 Nîmes Cedex 02, France. Phone: (33) 4 66 68 32 31. Fax: (33) 4 66 68 38 24. E-mail: albert.sotto{at}chu-nimes.fr.

Journal of Clinical Microbiology, July 2005, p. 3512-3515, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3512-3515.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Depardieu, F., Foucault, M.-L., Bell, J., Dubouix, A., Guibert, M., Lavigne, J.-P., Levast, M., Courvalin, P. (2009). New Combinations of Mutations in VanD-Type Vancomycin-Resistant Enterococcus faecium, Enterococcus faecalis, and Enterococcus avium Strains. Antimicrob. Agents Chemother. 53: 1952-1963 [Abstract] [Full Text]  


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