This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Santos, N. Articles by Hoshino, Y. Search for Related Content PubMed PubMed Citation Articles by Santos, N. Articles by Hoshino, Y.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, August 2005, p. 4064-4069, Vol. 43, No. 8
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.8.4064-4069.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Predominance of Rotavirus Genotype G9 during the 1999, 2000, and 2002 Seasons among Hospitalized Children in the City of Salvador, Bahia, Brazil: Implications for Future Vaccine Strategies

Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21.941-590, Brazil,¹ Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-8026,² Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, BA 40.110-100, Brazil³

Received 29 January 2005/ Returned for modification 26 March 2005/ Accepted 30 April 2005

Two hundred eight of 648 (32%) diarrheal stool samples collected from hospitalized children under 5 years of age during a 3-year period (1999, 2000, and 2002) in the city of Salvador, in the state of Bahia, Brazil, were rotavirus positive. One hundred sixty-four of 208 (78.8%) rotavirus-positive samples had genotype G9 specificity, predominantly in association with P[8]. Other specificities detected were G1 (12.0%) and G4 (1.4%). Viruses with G2, G3, or P[4] specificity were not detected. Rotavirus genotype G9 predominated during each of the three seasons studied; it represented 89.2% of rotavirus strains detected in 1999, 85.3% in 2000, and 74.5% in 2002. G1 viruses (the globally most common G type) have a unique epidemiological characteristic of maintaining predominance during multiple consecutive rotavirus seasons. We have shown in this study for the first time that the G9 viruses also have a similar epidemiological characteristic, albeit for a shorter period of surveillance. The next generation of rotavirus vaccines will need to provide adequate protection against disease caused by G9 viruses.

This article has been cited by other articles:

• Ferrer, S. R, Strina, A., Jesus, S. R, Ribeiro, H. C, Cairncross, S., Rodrigues, L. C, Barreto, M. L (2008). A hierarchical model for studying risk factors for childhood diarrhoea: a case-control study in a middle-income country. Int J Epidemiol 37: 805-815 [Abstract] [Full Text]  
• Tcheremenskaia, O., Marucci, G., De Petris, S., Ruggeri, F. M., Dovecar, D., Sternak, S. L., Matyasova, I., Dhimolea, M. K., Mladenova, Z., Fiore, L., and the Rotavirus Study Group, (2007). Molecular Epidemiology of Rotavirus in Central and Southeastern Europe. J. Clin. Microbiol. 45: 2197-2204 [Abstract] [Full Text]  
• Mascarenhas, J. D. P., Leite, J. P. G., Lima, J. C., Heinemann, M. B., Oliveira, D. S., Araujo, I. T., Soares, L. S., Gusmao, R. H. P., Gabbay, Y. B., Linhares, A. C. (2007). Detection of a neonatal human rotavirus strain with VP4 and NSP4 genes of porcine origin. J Med Microbiol 56: 524-532 [Abstract] [Full Text]