This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Santos, N.
Right arrow Articles by Hoshino, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Santos, N.
Right arrow Articles by Hoshino, Y.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, August 2005, p. 4064-4069, Vol. 43, No. 8
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.8.4064-4069.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Predominance of Rotavirus Genotype G9 during the 1999, 2000, and 2002 Seasons among Hospitalized Children in the City of Salvador, Bahia, Brazil: Implications for Future Vaccine Strategies

Norma Santos,1,2* Eduardo M. Volotão,1 Caroline C. Soares,1 Gúbio S. Campos,3 Silvia Ines Sardi,3 and Yasutaka Hoshino2

Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21.941-590, Brazil,1 Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-8026,2 Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, BA 40.110-100, Brazil3

Received 29 January 2005/ Returned for modification 26 March 2005/ Accepted 30 April 2005

Two hundred eight of 648 (32%) diarrheal stool samples collected from hospitalized children under 5 years of age during a 3-year period (1999, 2000, and 2002) in the city of Salvador, in the state of Bahia, Brazil, were rotavirus positive. One hundred sixty-four of 208 (78.8%) rotavirus-positive samples had genotype G9 specificity, predominantly in association with P[8]. Other specificities detected were G1 (12.0%) and G4 (1.4%). Viruses with G2, G3, or P[4] specificity were not detected. Rotavirus genotype G9 predominated during each of the three seasons studied; it represented 89.2% of rotavirus strains detected in 1999, 85.3% in 2000, and 74.5% in 2002. G1 viruses (the globally most common G type) have a unique epidemiological characteristic of maintaining predominance during multiple consecutive rotavirus seasons. We have shown in this study for the first time that the G9 viruses also have a similar epidemiological characteristic, albeit for a shorter period of surveillance. The next generation of rotavirus vaccines will need to provide adequate protection against disease caused by G9 viruses.

* Corresponding author. Mailing address: Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitária, CCS—Bl. I, Ilha do Fundão, Rio de Janeiro, RJ 21.941-590, Brazil. Phone: 55 21 2562-6749. Fax: 55 21 2560-8344. E-mail: nsantos{at}micro.ufrj.br.

Journal of Clinical Microbiology, August 2005, p. 4064-4069, Vol. 43, No. 8
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.8.4064-4069.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Aparecido Nunes, A., Marques de Mello, L., Neiva Parrode, R., Paulo Maneira Bittar, J., Luiz da Silva Domingues, A. (2009). Prevalence of Rotavirus in Acute Diarrhea and its Association with Clinical Signs and Symptoms. J Trop Pediatr 0: fmp091v1-fmp091 [Abstract] [Full Text]  
  • Ferrer, S. R, Strina, A., Jesus, S. R, Ribeiro, H. C, Cairncross, S., Rodrigues, L. C, Barreto, M. L (2008). A hierarchical model for studying risk factors for childhood diarrhoea: a case-control study in a middle-income country. Int J Epidemiol 37: 805-815 [Abstract] [Full Text]  
  • Tcheremenskaia, O., Marucci, G., De Petris, S., Ruggeri, F. M., Dovecar, D., Sternak, S. L., Matyasova, I., Dhimolea, M. K., Mladenova, Z., Fiore, L., and the Rotavirus Study Group, (2007). Molecular Epidemiology of Rotavirus in Central and Southeastern Europe. J. Clin. Microbiol. 45: 2197-2204 [Abstract] [Full Text]  
  • Mascarenhas, J. D. P., Leite, J. P. G., Lima, J. C., Heinemann, M. B., Oliveira, D. S., Araujo, I. T., Soares, L. S., Gusmao, R. H. P., Gabbay, Y. B., Linhares, A. C. (2007). Detection of a neonatal human rotavirus strain with VP4 and NSP4 genes of porcine origin. J Med Microbiol 56: 524-532 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»