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Molecular Profiling and Phenotype Analysis of Escherichia coli O26:H11 and O26:NM: Secular and Geographic Consistency of Enterohemorrhagic and Enteropathogenic Isolates

Institute for Hygiene and the National Consulting Laboratory on Hemolytic Uremic Syndrome, University Hospital Münster, Robert Koch Str. 41, 48149 Münster, Germany,¹ Departments of Pediatrics and Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri²

Received 9 April 2005/ Accepted 17 April 2005

Fifty-eight enterohemorrhagic Escherichia coli O26:H11 or O26:NM (nonmotile) strains and 44 atypical enteropathogenic E. coli O26:H11 or O26:NM strains isolated from patients in 11 countries during 52 years share a common pool of non-stx virulence genes, fitness loci, and genotypic and phenotypic diagnostic markers. These findings indicate close relatedness between these pathotypes and provide a basis for their clinical laboratory diagnosis.

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