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Journal of Clinical Microbiology, August 2005, p. 4266-4268, Vol. 43, No. 8
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.8.4266-4268.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Phenotypic and Genotypic Mupirocin Resistance among Staphylococci Causing Prosthetic Joint Infection

Margalida Rotger,1 Andrej Trampuz,1 Kerryl E. Piper,1 James M. Steckelberg,1 and Robin Patel1,2*

Division of Infectious Diseases, Department of Internal Medicine,1 Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota2

Received 10 December 2004/ Returned for modification 9 February 2005/ Accepted 19 April 2005

Mupirocin MICs and mupA presence were determined in 108 staphylococci causing prosthetic joint infection. Zero of 35 isolates (0%) of methicillin-susceptible Staphylococcus aureus, 4/15 (27%) methicillin-resistant S. aureus isolates, 3/16 (19%) methicillin-susceptible coagulase-negative staphylococci, and 11/42 (26%) methicillin-resistant coagulase-negative staphylococci were mupirocin resistant. mupA was detected in all five high-level mupirocin-resistant staphylococci and one mupirocin-susceptible staphylococcus.

* Corresponding author. Mailing address: Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First St. SW, Rochester, MN 55905. Phone: (507) 255-6482. Fax: (507) 284-9066. E-mail: patel.robin{at}mayo.edu.

Journal of Clinical Microbiology, August 2005, p. 4266-4268, Vol. 43, No. 8
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.8.4266-4268.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Prokuski, L. (2008). Prophylactic Antibiotics in Orthopaedic Surgery. J Am Acad Orthop Surg 16: 283-293 [Abstract] [Full Text]  
  • Simor, A. E., Stuart, T. L., Louie, L., Watt, C., Ofner-Agostini, M., Gravel, D., Mulvey, M., Loeb, M., McGeer, A., Bryce, E., Matlow, A., and the Canadian Nosocomial Infection Surveillance, (2007). Mupirocin-Resistant, Methicillin-Resistant Staphylococcus aureus Strains in Canadian Hospitals. Antimicrob. Agents Chemother. 51: 3880-3886 [Abstract] [Full Text]  


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