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Journal of Clinical Microbiology, September 2005, p. 4858-4861, Vol. 43, No. 9
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.9.4858-4861.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Characterization of Mycobacterium tuberculosis Complex Isolates from Greek Patients with Sarcoidosis by Spoligotyping

Department of Histology-Embryology, School of Medicine, University of Athens, Greece,¹ Department of Anatomy-Physiology, Agricultural University, Athens, Greece,² Veterinary Research Institute, Brno, Czech Republic,³ Diagnostic Laboratory for Infectious Disease and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands⁴

Received 6 January 2005/ Returned for modification 16 February 2005/ Accepted 16 May 2005

Spoligotyping was undertaken with 38 Mycobacterium tuberculosis isolates from Greek sarcoidosis patients and 31 isolates from patients with tuberculosis. Fifty percent of the isolates from sarcoidosis patients and 16.13% of the isolates from patients with tuberculosis were represented by a unique pattern, whereas the remaining isolates belonged to seven shared types. Interestingly, half of the isolates from sarcoidosis patients did not resemble the spoligotypes of the isolates from patients with tuberculosis, most of which pertained to shared spoligotypes.

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