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Journal of Clinical Microbiology, September 2005, p. 4885-4888, Vol. 43, No. 9
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.9.4885-4888.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Regional Occurrence of Plasmid-Mediated Carbapenem-Hydrolyzing Oxacillinase OXA-58 in Acinetobacter spp. in Europe

Sophie Marqué,1 Laurent Poirel,1 Claire Héritier,1 Sylvain Brisse,2 Maria Dolores Blasco,1 Roxana Filip,3 Gabriela Coman,3 Thierry Naas,1 and Patrice Nordmann1*

Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Université Paris XI, K.-Bicêtre,1 Unité de Recherche de la Biodiversité des Pathogènes Bactériens Emergents, Institut Pasteur, Paris, France,2 University of Medicine and Pharmacy Gr. T. Popa, St. Maria Pediatric Hospital, Iasi, Romania3

Received 11 March 2005/ Returned for modification 23 May 2005/ Accepted 31 May 2005

The spread of the plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 was detected in Acinetobacter sp. clinical isolates from southern Europe, the Balkans, and central Turkey. It may contribute significantly to the emergence of carbapenem resistance in Acinetobacter spp., at least in this part of the world.


* Corresponding author. Mailing address: Service de Bactériologie-Virologie, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94275 Le-Kremlin-Bicêtre cedex, France. Phone: 33-1-45-21-36-32. Fax: 33-1-45-21-63-40. E-mail: nordmann.patrice{at}bct.ap-hop-paris.fr.


Journal of Clinical Microbiology, September 2005, p. 4885-4888, Vol. 43, No. 9
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.9.4885-4888.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.




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