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Journal of Clinical Microbiology, January 2006, p. 266-270, Vol. 44, No. 1
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.1.266-270.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Prevalence and Evolution of Methicillin-Resistant Staphylococcus aureus in Spanish Hospitals between 1996 and 2002

A. Vindel,1* P. Trincado,1 E. Gómez,1 R. Cabrera,1 T. Boquete,1 C. Solá,2 S. Valdezate,1 and J. A. Saez-Nieto1

Nosocomial Infectious Diseases Laboratory, Servicio de Bacteriología, Instituto de Salud Carlos III, Centro Nacional de Microbiología, 28220 Majadahonda, Madrid, Spain,1 Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Departamento de Bioquímica Clinica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, Pabellon Argentina, 5000 Córdoba, Argentina2

Received 26 August 2005/ Returned for modification 27 September 2005/ Accepted 7 October 2005

Pulsed-field gel electrophoretic analysis of 2,144 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from patients in Spanish hospitals over a 7-year period revealed 17 predominant profiles. Typing showed the replacement of Iberian clone E1 (ST247-MRSA-I) by two prevalent clones, E7 and E8, that are closely related to each other and have the same genetic background as ST125-MRSA-IV.

* Corresponding author. Mailing address: Nosocomial Infectious Diseases Laboratory, Instituto de Salud Carlos III, Centro Nacional de Microbiología, 28220 Majadahonda, Madrid, Spain. Phone: 34-91-8223666. Fax: 34-91-5097966. E-mail: avindel{at}isciii.es.

Journal of Clinical Microbiology, January 2006, p. 266-270, Vol. 44, No. 1
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.1.266-270.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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