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Journal of Clinical Microbiology, October 2006, p. 3797-3798, Vol. 44, No. 10
0095-1137/06/$08.00+0     doi:10.1128/JCM.01159-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Comparative Evaluation of Three Commercially Available Methodologies for Hepatitis C Virus Genotyping

Ted E. Schutzbank,1* Susan E. Sefers,2 Nicole Kahmann,1 Haijing Li,3 and Yi-Wei Tang2,3

CompuNet Clinical Laboratories, Dayton, Ohio,1 Departments of Pathology,2 Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee3

Received 5 June 2006/ Returned for modification 10 July 2006/ Accepted 31 July 2006

We compared the performances of three hepatitis C virus genotyping methodologies supplied by Bayer, Abbott, and Third Wave Technologies. Genotypes were determined for 136 of 137 specimens by the Bayer method, 121 of 137 specimens by the Invader assay, and only 77 of 137 specimens by the Abbott assay. All reported genotypes were concordant by all three methods.


* Corresponding author. Mailing address: CompuNet Clinical Laboratories, 2308 Sandridge Rd., Dayton, OH 45439. Phone: (937) 290-7326. Fax: (937) 297-8229. E-mail: ted.e.schutzbank{at}questdiagnostics.com.


Journal of Clinical Microbiology, October 2006, p. 3797-3798, Vol. 44, No. 10
0095-1137/06/$08.00+0     doi:10.1128/JCM.01159-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.