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Journal of Clinical Microbiology, October 2006, p. 3799-3803, Vol. 44, No. 10
0095-1137/06/$08.00+0     doi:10.1128/JCM.01482-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Acquisition of Helicobacter pylori Infection in Rhesus Macaques Is Most Consistent with Oral-Oral Transmission

Jay V. Solnick,1,2,3* Julie Fong,3 Lori M. Hansen,3 Kikuko Chang,3 Don R. Canfield,4 and Julie Parsonnet5

Departments of Internal Medicine,1 Medical Microbiology & Immunology,2 Center for Comparative Medicine,3 California National Primate Research Center, University of California, Davis, Davis, California,4 Departments of Internal Medicine and Health Research and Policy, Stanford University Medical School, Stanford, California5

Received 18 July 2006/ Accepted 23 July 2006

Socially housed rhesus monkeys rapidly acquired Helicobacter pylori infection, although the organism was rarely cultivated from saliva, feces, or the environment. Since the concentrations of H. pylori in vomit were compatible with what is known about the infectious dose, our results are most consistent with an oral-oral means of transmission.


* Corresponding author. Mailing address: Center for Comparative Medicine, University of California, Davis, Davis, CA 95616. Phone: (530) 752-1333. Fax: (530) 752-7914. E-mail: jvsolnick{at}ucdavis.edu.


Journal of Clinical Microbiology, October 2006, p. 3799-3803, Vol. 44, No. 10
0095-1137/06/$08.00+0     doi:10.1128/JCM.01482-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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