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Journal of Clinical Microbiology, October 2006, p. 3814-3818, Vol. 44, No. 10
0095-1137/06/$08.00+0 doi:10.1128/JCM.00881-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Los Angeles County/University of Southern California Medical Center,1 USC Keck School of Medicine, Los Angeles, California2
Received 26 April 2006/ Returned for modification 22 June 2006/ Accepted 3 August 2006
Daptomycin inhibited 67 of 70 clinical isolates of Bacillus species at
1 µg/ml and 100% of them at
2 µg/ml. It showed bactericidal activity similar to that of ciprofloxacin against vegetative cells but not against spores. For 2 strains, the ciprofloxacin MICs were >4 g/ml, and 10 strains were resistant to erythromycin.
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