This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bogaerts, P.
Right arrow Articles by Glupczynski, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bogaerts, P.
Right arrow Articles by Glupczynski, Y.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, November 2006, p. 4189-4192, Vol. 44, No. 11
0095-1137/06/$08.00+0     doi:10.1128/JCM.00796-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Outbreak of Infection by Carbapenem-Resistant Acinetobacter baumannii Producing the Carbapenemase OXA-58 in Belgium{triangledown}

Pierre Bogaerts,1* Thierry Naas,2 Ingrid Wybo,3 Caroline Bauraing,1 Oriane Soetens,3 Denis Piérard,3 Patrice Nordmann,2 and Youri Glupczynski1

Laboratoire de Bactériologie, Cliniques Universitaires UCL de Mont-Godinne, B-5530 Yvoir, Belgium,1 Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique-Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Université Paris XI, Le Kremlin-Bicêtre, France,2 Dienst Microbiologie en Ziekenhuishygiëne, Academisch Ziekenhuis Vrije Universiteit Brussel, B-1090 Brussels, Belgium3

Received 13 April 2006/ Returned for modification 8 August 2006/ Accepted 25 August 2006

Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 17 patients between September 2004 and August 2005 at the Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium. These multidrug-resistant isolates, which belonged to a single clone, remained susceptible to colistin and tigecycline only and produced the carbapenem-hydrolyzing oxacillinase OXA-58. This study highlights the importance of the intercountry spread of this ß-lactamase-mediated resistance mechanism and its epidemic evolution.

* Corresponding author. Mailing address: Laboratoire de Bactériologie, Cliniques Universitaires UCL de Mont-Godinne, 1, Av. Dr Gaston Thérasse, B-5530 Yvoir, Belgium. Phone: 32-81-42-32-41. Fax: 32-81-42-32-46. E-mail: pierre.bogaerts{at}mont.ucl.ac.be.

{triangledown} Published ahead of print on 6 September 2006.

Journal of Clinical Microbiology, November 2006, p. 4189-4192, Vol. 44, No. 11
0095-1137/06/$08.00+0     doi:10.1128/JCM.00796-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Peleg, A. Y., Seifert, H., Paterson, D. L. (2008). Acinetobacter baumannii: Emergence of a Successful Pathogen. Clin. Microbiol. Rev. 21: 538-582 [Abstract] [Full Text]  
  • Karageorgopoulos, D. E., Kelesidis, T., Kelesidis, I., Falagas, M. E. (2008). Tigecycline for the treatment of multidrug-resistant (including carbapenem-resistant) Acinetobacter infections: a review of the scientific evidence. J Antimicrob Chemother 62: 45-55 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»