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Journal of Clinical Microbiology, November 2006, p. 4211-4213, Vol. 44, No. 11
0095-1137/06/$08.00+0     doi:10.1128/JCM.01304-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Cholera Due to Altered El Tor Strains of Vibrio cholerae O1 in Bangladesh{triangledown}

G. Balakrish Nair,1* Firdausi Qadri,1 Jan Holmgren,2 Ann-Mari Svennerholm,2 Ashrafus Safa,1 Nurul A. Bhuiyan,1 Q. Shafi Ahmad,1 Shah M. Faruque,1 A. S. G. Faruque,1 Yoshifumi Takeda,3 and David A. Sack1

ICDDR,B: Centre for Health and Population Research, Mohakhali, Dhaka, Bangladesh,1 Department of Microbiology and Immunology, The Sahlgrenska Academy at Goteborg University & Gothenburg University Vaccine Research Institute, Goteborg, Sweden,2 Cine-Science Laboratory, Itabashi, Tokyo, Japan3

Received 26 June 2006/ Returned for modification 1 August 2006/ Accepted 14 August 2006

We determined the types of cholera toxin (CT) produced by a collection of 185 Vibrio cholerae O1 strains isolated in Bangladesh over the past 45 years. All of the El Tor strains of V. cholerae O1 isolated since 2001 produced CT of the classical biotype, while those isolated before 2001 produced CT of the El Tor biotype.

* Corresponding author. Mailing address: Laboratory Sciences Division, ICDDR,B: Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh. Phone: 880-3-9886464. Fax: 880-2-8812529. E-mail: gbnair{at}icddrb.org.

{triangledown} Published ahead of print on 6 September 2006.

Journal of Clinical Microbiology, November 2006, p. 4211-4213, Vol. 44, No. 11
0095-1137/06/$08.00+0     doi:10.1128/JCM.01304-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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