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Journal of Clinical Microbiology, November 2006, p. 4227-4228, Vol. 44, No. 11
0095-1137/06/$08.00+0 doi:10.1128/JCM.00722-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Division of Infectious Disease,1 Division of Microbiology, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, New York 110422
Received 5 April 2006/ Returned for modification 26 June 2006/ Accepted 1 September 2006
We investigated the in vitro susceptibilities of 23 Propionibacterium acnes ophthalmic isolates to ertapenem, meropenem, and cefepime by utilizing the Etest. The MICs ranged from 0.094 µg/ml to 0.75 µg/ml, 0.094 µg/ml to 1.5 µg/ml, and 1 µg/ml to 12 µg/ml for ertapenem, meropenem, and cefepime, respectively. Based on our excellent in vitro carbapenem susceptibility results, in vivo studies using ertapenem and meropenem in a rabbit model of P. acnes endophthalmitis are warranted.
Published ahead of print on 13 September 2006.
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