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Journal of Clinical Microbiology, December 2006, p. 4564-4565, Vol. 44, No. 12
0095-1137/06/$08.00+0     doi:10.1128/JCM.00981-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Effect of Endocervical-Specimen Adequacy on Detection of Chlamydia trachomatis by the APTIMA COMBO 2 Assay{triangledown}

C. K. Rogers,1* B. J. Wood,2 P. Rizzo,2 and C. A. Gaydos2

Wyoming Public Health Laboratory, 517 Hathaway Bldg., 2300 Capitol Ave., Cheyenne, Wyoming 82002,1 Johns Hopkins University, 1159 Ross Bldg., 720 Rutland Ave., Baltimore, Maryland 212052

Received 10 May 2006/ Returned for modification 10 July 2006/ Accepted 9 October 2006

Six hundred one endocervical specimens were analyzed for Chlamydia trachomatis by the APTIMA Combo 2 assay and evaluated for columnar epithelial cell adequacy by direct fluorescent-antibody staining. With 5.5% positive adequate and 7.8% positive inadequate specimens (P = 0.27), the study suggested no difference in positivity rates due to specimen adequacy when this amplified technology was used.

* Corresponding author. Mailing address: Wyoming Public Health Laboratory, 517 Hathaway Bldg., 2300 Capitol Ave., Cheyenne, WY 82002. Phone: (307) 777-7431. Fax: (307) 777-6422. E-mail: croger{at}state.wy.us.

{triangledown} Published ahead of print on 25 October 2006.

Journal of Clinical Microbiology, December 2006, p. 4564-4565, Vol. 44, No. 12
0095-1137/06/$08.00+0     doi:10.1128/JCM.00981-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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