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Journal of Clinical Microbiology, December 2006, p. 4569-4571, Vol. 44, No. 12
0095-1137/06/$08.00+0     doi:10.1128/JCM.01979-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Evaluation of Entamoeba histolytica Antigen and Antibody Point-of-Care Tests for the Rapid Diagnosis of Amebiasis{triangledown}

Megan Leo,1 Rashidul Haque,2 Mamun Kabir,2 Shantanu Roy,2 Rita Marie Lahlou,1 Dinesh Mondal,2 Egbert Tannich,3 and William A. Petri Jr.1*

University of Virginia, Charlottesville, Virginia,1 ICDDR,B, Dhaka, Bangladesh,2 Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany3

Received 24 September 2006/ Accepted 29 September 2006

The bedside diagnosis of amebiasis could improve patient care. In Bangladesh and Vietnam, a novel and simple-to-use Entamoeba histolytica rapid antigen test had 97% sensitivity and 100% specificity compared to the results of a standard enzyme-linked immunosorbent assay antigen detection method, and a rapid antibody test had 89 to 100% sensitivity and 89 to 95% specificity.

* Corresponding author. Mailing address: University of Virginia Health System, P.O. Box 801340, Charlottesville, VA 22908-1340. Phone: (434) 924-5621. Fax: (434) 924-0075. E-mail: wap3g{at}virginia.edu.

{triangledown} Published ahead of print on 11 October 2006.

Journal of Clinical Microbiology, December 2006, p. 4569-4571, Vol. 44, No. 12
0095-1137/06/$08.00+0     doi:10.1128/JCM.01979-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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