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Journal of Clinical Microbiology, February 2006, p. 604-606, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.604-606.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Sequence Variability of Human Erythroviruses Present in Bone Marrow of Brazilian Patients with Various Parvovirus B19-Related Hematological Symptoms

Sabri Sanabani,1 Walter Kleine Neto,1,2 Juliana Pereira,2 and Ester Cerdeira Sabino1*

Fundação Pró-Sangue, Hemocentro, São Paulo, Brazil,1 Department of Hematology, University of São Paulo, São Paulo, Brazil2

Received 13 July 2005/ Returned for modification 23 August 2005/ Accepted 14 November 2005

The presence of erythrovirus infections was investigated by PCR with bone marrow samples of patients with various parvovirus B19-related hematological symptoms. Erythrovirus DNA was found in 17.3% (12/69) of patients. Phylogenetic analysis revealed that five strains cluster with genotype 1, one clusters with genotype 2, and six cluster with genotype 3. Our study is the first to document the presence of the three erythrovirus genotypes in Brazil.

* Corresponding author. Mailing address: Molecular Biology Laboratory, Fundação Pró-Sangue, Hemocentro de São Paulo, Brazil, Av. Eneas de Carvalho Aguiar, 155, 1° andar, São Paulo, Brazil 05403 000. Fax: 5511 30888317. Phone: 5511 30615544, ext. 221. E-mail: sabinoec{at}uol.com.br.

Journal of Clinical Microbiology, February 2006, p. 604-606, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.604-606.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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Copyright © 2006 by the American Society for Microbiology. All rights reserved.