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Journal of Clinical Microbiology, February 2006, p. 632-634, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.632-634.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Multilocus Genotyping of Cryptosporidium sp. Isolates from Human Immunodeficiency Virus-Infected Individuals in South India

Dheepa Muthusamy,1 Sitara S. Rao,2 Sasirekha Ramani,2 Bindhu Monica,2 Indrani Banerjee,2 Ooriapadickal C. Abraham,3 Dilip C. Mathai,3 Beryl Primrose,4 Jayaprakash Muliyil,4 Christine A. Wanke,5 Honorine D. Ward,5 and Gagandeep Kang2*

Departments of Clinical Microbiology,1 Gastrointestinal Sciences,2 Medicine,3 Community Health, Christian Medical College, Vellore, TN 632004, India,4 Division of Geographic Medicine and Infectious Diseases, Tufts-New England Medical Center, Tufts University School of Medicine, 750 Washington St., Boston, Massachusetts 021115

Received 21 September 2005/ Accepted 28 September 2005

This study characterized cryptosporidial infections in 48 human immunodeficiency virus-infected individuals in India by multilocus genotyping. Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads.

* Corresponding author. Mailing address: Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632004, India. Phone: 91-416-2282052. Fax: 91-416-2232035. E-mail: gkang{at}cmcvellore.ac.in.

Journal of Clinical Microbiology, February 2006, p. 632-634, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.632-634.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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