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Journal of Clinical Microbiology, February 2006, p. 643-645, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.643-645.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Etiologic Diagnosis of Adult Bacterial Pneumonia by Culture and PCR Applied to Respiratory Tract Samples

Kristoffer Strålin,1* Eva Törnqvist,2 Margit Staum Kaltoft,3 Per Olcén,2 and Hans Holmberg1

Departments of Infectious Diseases,1 Clinical Microbiology, Örebro University Hospital, Örebro, Sweden,2 Streptococcus Unit, Division of Microbiology and Diagnostics, Statens Serum Institut, Copenhagen, Denmark3

Received 8 September 2005/ Accepted 8 November 2005

Respiratory culture and multiplex PCR for Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, and Chlamydophila pneumoniae were applied to sputum, nasopharyngeal swabs, and nasopharyngeal aspirates from 235 adult patients with community-acquired pneumonia and 113 controls. Both culture and multiplex PCR performed well with the different samples and appear to be useful as diagnostic tools.

* Corresponding author. Mailing address: Department of Infectious Diseases, Örebro University Hospital, SE-70185 Örebro, Sweden. Phone: 46196023619. Fax: 4619184855. E-mail: kristoffer.stralin{at}orebroll.se.

Journal of Clinical Microbiology, February 2006, p. 643-645, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.643-645.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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