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Journal of Clinical Microbiology, March 2006, p. 1123-1126, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1123-1126.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Identification of Human H1N2 and Human-Swine Reassortant H1N2 and H1N1 Influenza A Viruses among Pigs in Ontario, Canada (2003 to 2005){dagger}

Alexander I. Karasin,1 Suzanne Carman,2 and Christopher W. Olsen1*

Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin—Madison, Madison, Wisconsin,1 Animal Health Laboratory, Laboratory Services Division, University of Guelph, Box 3612, Guelph, Ontario, Canada2

Received 18 July 2005/ Returned for modification 28 October 2005/ Accepted 11 December 2005

Since 2003, three novel genotypes of H1 influenza viruses have been recovered from Canadian pigs, including a wholly human H1N2 virus and human-swine reassortants. These isolates demonstrate that human-lineage H1N2 viruses are infectious for pigs and that viruses with a human PB1/swine PA/swine PB2 polymerase complex can replicate in pigs.


* Corresponding author. Mailing address: Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Dr., Madison, WI 53706. Phone: (608) 265-8681. Fax: (608) 263-0438. E-mail: olsenc{at}svm.vetmed.wisc.edu.

{dagger} Supplemental material for this article may be found at http://jcm.asm.org/.


Journal of Clinical Microbiology, March 2006, p. 1123-1126, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1123-1126.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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Copyright © 2006 by the American Society for Microbiology. All rights reserved.