This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bonora, M. G.
Right arrow Articles by Fontana, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bonora, M. G.
Right arrow Articles by Fontana, R.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, March 2006, p. 1153-1155, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1153-1155.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Emergence of Linezolid Resistance in the Vancomycin-Resistant Enterococcus faecium Multilocus Sequence Typing C1 Epidemic Lineage

Maria Grazia Bonora,1 Maurizio Solbiati,2 Erminia Stepan,3 Antonella Zorzi,3 Aldo Luzzani,4 Maria Rosaria Catania,5 and Roberta Fontana1,3*

Dipartimento di Patologia, Sezione di Microbiologia, Università di Verona,1 Osservatorio Epidemiologico, Azienda Ospedaliera di Verona,2 Servizio di Microbiologia, Immunologia e Virologia, Azienda Ospedaliera di Verona,3 Unità di Rianimazione e Terapia Intensiva, Azienda Ospedaliera di Verona, Verona, Italy,4 Dipartimento di Biologia Cellulare e Molecolare, Università di Napoli Federico II, Napoli, Italy5

Received 27 October 2005/ Returned for modification 1 December 2005/ Accepted 10 January 2006

A relatively high rate of vancomycin-resistant Enterococcus faecium not susceptible to linezolid was observed in intensive care unit patients. Linezolid-resistant isolates carried the G2576T mutation in the 23S rRNA gene, belonged to different clones, and shared the same allelic profile, which clusters in the C1 multilocus sequence typing epidemic lineage.

* Corresponding author. Mailing address: Dipartimento di Patologia, Sezione di Microbiologia, Università di Verona, Strada Le Grazie 8, 37100 Verona, Italy. Phone: 39 045 8027191. Fax: 39 045 584606. E-mail: roberta.fontana{at}univr.it.

Journal of Clinical Microbiology, March 2006, p. 1153-1155, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1153-1155.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Cian, F., Luzzati, R., Deiana, M. L., Ferrantelli, N., Tonin, E., Lagatolla, C., Dolzani, L. (2009). Colonization of the tip of a thoracic catheter by Enterococcus faecalis resistant to vancomycin and linezolid. J Med Microbiol 58: 1118-1121 [Abstract] [Full Text]  
  • Gould, F. K., Brindle, R., Chadwick, P. R., Fraise, A. P., Hill, S., Nathwani, D., Ridgway, G. L., Spry, M. J., Warren, R. E., on behalf of the MRSA Working Party of the British, (2009). Guidelines (2008) for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the United Kingdom. J Antimicrob Chemother 63: 849-861 [Abstract] [Full Text]  
  • Lawrence, L., Danese, P., DeVito, J., Franceschi, F., Sutcliffe, J. (2008). In Vitro Activities of the Rx-01 Oxazolidinones against Hospital and Community Pathogens. Antimicrob. Agents Chemother. 52: 1653-1662 [Abstract] [Full Text]  
  • Bailey, J., Summers, K. M. (2008). Dalbavancin: A new lipoglycopeptide antibiotic. Am J Health Syst Pharm 65: 599-610 [Abstract] [Full Text]  
  • Werner, G., Bartel, M., Wellinghausen, N., Essig, A., Klare, I., Witte, W., Poppert, S. (2007). Detection of Mutations Conferring Resistance to Linezolid in Enterococcus spp. by Fluorescence In Situ Hybridization. J. Clin. Microbiol. 45: 3421-3423 [Abstract] [Full Text]  
  • Grare, M., Mourer, M., Fontanay, S., Regnouf-de-Vains, J.-B., Finance, C., Duval, R. E. (2007). In vitro activity of para-guanidinoethylcalix[4]arene against susceptible and antibiotic-resistant Gram-negative and Gram-positive bacteria. J Antimicrob Chemother 60: 575-581 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»