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Journal of Clinical Microbiology, April 2006, p. 1540-1542, Vol. 44, No. 4
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.4.1540-1542.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

A Sensor To Detect the Early Stages in the Development of Crystalline Proteus mirabilis Biofilm on Indwelling Bladder Catheters

D. J. Stickler,1* S. M. Jones,1 G. O. Adusei,2 and M. G. Waters2

Cardiff School of Biosciences,1 Cardiff School of Dentistry, Cardiff University, Cardiff, Wales, United Kingdom2

Received 21 October 2005/ Accepted 16 December 2005

A simple sensor has been developed to detect the early stages of urinary catheter encrustation and avoid the clinical crises induced by catheter blockage. In laboratory models of colonization by Proteus mirabilis, the sensor signaled encrustation at an average time of 43 h before catheters were blocked with crystalline biofilm.

* Corresponding author. Mailing address: Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, United Kingdom. Phone: 44 29 20874311. Fax: 44 29 20784305. E-mail: stickler{at}cardiff.ac.uk.

Journal of Clinical Microbiology, April 2006, p. 1540-1542, Vol. 44, No. 4
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.4.1540-1542.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Jacobsen, S. M., Stickler, D. J., Mobley, H. L. T., Shirtliff, M. E. (2008). Complicated Catheter-Associated Urinary Tract Infections Due to Escherichia coli and Proteus mirabilis. Clin. Microbiol. Rev. 21: 26-59 [Abstract] [Full Text]  


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