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Journal of Clinical Microbiology, April 2006, p. 1550-1554, Vol. 44, No. 4
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.4.1550-1554.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Seroprevalence and Molecular Epidemiology of Human T-Cell Leukemia Virus Type 1 (HTLV-1) and HTLV-2 in Blood Donors from Dakar, Senegal

Saliou Diop,1 Sara Calattini,2 Julienne Abah-Dakou,1 Doudou Thiam,1 Lamine Diakhaté,1 and Antoine Gessain2*

Centre National de Transfusion Sanguine, Ave. Cheikh Anta Diop, Fann, BP 5002 Dakar, Sénégal,1 Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Département Ecosytèmes et Epidémiologie des Maladies Infectieuses, Institut Pasteur, 75015 Paris, France2

Received 24 October 2005/ Returned for modification 13 January 2006/ Accepted 20 January 2006

In 2002, human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 seroprevalence was 0.16% (8/4,900) in blood donors from Dakar, Senegal. Most of the positive donors originated from the country’s southern region. Seven donors were infected by HTLV-1 (of cosmopolitan subtype), and one was infected by HTLV-2. These data highlight the problem of transfusion safety in this area where HTLV-1-associated lymphoproliferative and neurological diseases are endemic.

* Corresponding author. Mailing address: Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Département Ecosytèmes et Epidémiologie des Maladies Infectieuses, Batiment Lwoff, Institut Pasteur, 25-28 Rue du Dr. Roux, 75724 Paris, Cedex 15, France. Phone: 33 (0)1 45 68 89 37. Fax: 33 (0)1 40 61 34 65. E-mail: agessain{at}pasteur.fr.

Journal of Clinical Microbiology, April 2006, p. 1550-1554, Vol. 44, No. 4
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.4.1550-1554.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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