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Molecular Characterization and Drug Resistance Testing of Mycobacterium tuberculosis Isolates from Chad

Laboratoire de Recherches Vétérinaires et Zootechniques de Farcha, N’Djaména, Chad,¹ Swiss Tropical Institute, Basel, Switzerland,² Department of Medical Microbiology, Kantonsspital Luzern, Luzern, Switzerland,³ National Center for Mycobacteria, University of Zurich, Zurich, Switzerland⁴

Received 2 February 2006/ Accepted 6 February 2006

The molecular characterizations of the first 40 Mycobacterium tuberculosis isolates from Chad revealed a high proportion of isolates of the Cameroon family (33%), of which one isolate showed a monodrug resistance. In total, 9/33 (27%) isolates were resistant to isoniazid. The implications of these findings are discussed.