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Journal of Clinical Microbiology, April 2006, p. 1575-1577, Vol. 44, No. 4
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.4.1575-1577.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Molecular Characterization and Drug Resistance Testing of Mycobacterium tuberculosis Isolates from Chad

Colette Diguimbaye,1 Markus Hilty,2* Richard Ngandolo,1 Hassane H. Mahamat,1 Gaby E. Pfyffer,3 Franca Baggi,4 Marcel Tanner,2 Esther Schelling,2 and Jakob Zinsstag2

Laboratoire de Recherches Vétérinaires et Zootechniques de Farcha, N’Djaména, Chad,1 Swiss Tropical Institute, Basel, Switzerland,2 Department of Medical Microbiology, Kantonsspital Luzern, Luzern, Switzerland,3 National Center for Mycobacteria, University of Zurich, Zurich, Switzerland4

Received 2 February 2006/ Accepted 6 February 2006

The molecular characterizations of the first 40 Mycobacterium tuberculosis isolates from Chad revealed a high proportion of isolates of the Cameroon family (33%), of which one isolate showed a monodrug resistance. In total, 9/33 (27%) isolates were resistant to isoniazid. The implications of these findings are discussed.

* Corresponding author. Mailing address: Swiss Tropical Institute, Socinstrasse 57, P.O. Box CH 4002, Basel, Switzerland. Phone: 41 61 2718139. Fax: 41 61 2848139. E-mail: Markus.Hilty{at}unibas.ch.

Journal of Clinical Microbiology, April 2006, p. 1575-1577, Vol. 44, No. 4
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.4.1575-1577.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Baboolal, S., Millet, J., Akpaka, P. E., Ramoutar, D., Rastogi, N. (2009). First Insight into Mycobacterium tuberculosis Epidemiology and Genetic Diversity in Trinidad and Tobago. J. Clin. Microbiol. 47: 1911-1914 [Abstract] [Full Text]  


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