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Journal of Clinical Microbiology, May 2006, p. 1867-1868, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1867-1868.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Lack of Association between the Presence of the pVir Plasmid and Bloody Diarrhea in Campylobacter jejuni Enteritis

R. P. L. Louwen,1* A. van Belkum,1 J. A. Wagenaar,2 Y. Doorduyn,3 R. Achterberg,3 and H. P. Endtz1

Department of Microbiology and Infectious Diseases, Erasmus MC, University Medical Center, Rotterdam, The Netherlands,1 Animal Sciences Group, Lelystad, The Netherlands,2 RIVM, Lelystad, The Netherlands3

Received 9 December 2005/ Returned for modification 5 January 2006/ Accepted 27 February 2006

The main mechanisms by which Campylobacter jejuni causes diarrhea are unknown. In contrast to a recent communication, we report here the absence of an association with the plasmid pVir in patients infected with C. jejuni who developed bloody diarrhea in The Netherlands, and we suggest a role for other virulence determinants.

* Corresponding author. Mailing address: Department Medical Microbiology and Infectious diseases, Erasmus MC, University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. Phone: 31-10-4632176. Fax: 31-10-4632171. E-mail: r.louwen{at}erasmusmc.nl.

Journal of Clinical Microbiology, May 2006, p. 1867-1868, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1867-1868.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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