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Journal of Clinical Microbiology, May 2006, p. 1903-1904, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1903-1904.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Early Diagnosis of Acanthamoeba Infection during Routine Cytological Examination of Cerebrospinal Fluid

Franz Petry,1*,{dagger} Michael Torzewski,2,{dagger} Jürgen Bohl,3 Thomas Wilhelm-Schwenkmezger,4 Patrick Scheid,5 Julia Walochnik,6 Rolf Michel,5 Lothar Zöller,5 Konrad J. Werhahn,4 Sucharit Bhakdi,1 and Karl J. Lackner2

Institute of Medical Microbiology and Hygiene,1 Institute of Clinical Chemistry and Laboratory Medicine,2 Department of Neuropathology,3 Department of Neurology, Johannes Gutenberg University, Mainz, Germany,4 Medical Parasitology Laboratory, Central Institute of the Bundeswehr Medical Service, Koblenz, Germany,5 Department of Medical Parasitology, Medical University of Vienna, Vienna, Austria6

Received 25 November 2005/ Returned for modification 18 January 2006/ Accepted 9 March 2006

Early identification of Acanthamoeba in cerebrospinal fluid is mandatory to prevent fatal granulomatous amebic encephalitis. In the case presented here amebic trophozoites were detected in a routine cerebrospinal fluid sample. The antibiotic treatment and the apparently low virulence of this isolate were responsible for the benign progression of the infection.

* Corresponding author. Mailing address: Institute of Medical Microbiology and Hygiene, Johannes Gutenberg University, D-55101 Mainz, Germany. Phone: 49-6131-393 3139. Fax: 49-6131-393 3439. E-mail: fpetry{at}mail.uni-mainz.de.

{dagger} These authors contributed equally to the work.

Journal of Clinical Microbiology, May 2006, p. 1903-1904, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1903-1904.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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