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Journal of Clinical Microbiology, May 2006, p. 1912-1914, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1912-1914.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Spondylodiscitis Caused by Candida krusei: Case Report and Susceptibility Patterns

Javier Pemán,1* Isidro Jarque,2 María Bosch,1 Emilia Cantón,3 Miguel Salavert,4 Rosario de Llanos,5 and Araceli Molina1

Microbiology Department, La Fe University Hospital, Av. Campanar 21, 46009 Valencia, Spain,1 Hematology Department, La Fe University Hospital, Av. Campanar 21, 46009 Valencia, Spain,2 Microbiology Experimental Unit, La Fe University Hospital, Av. Campanar 21, 46009 Valencia, Spain,3 Infectious Diseases Unit, La Fe University Hospital, Av. Campanar 21, 46009 Valencia, Spain,4 IATA (CSIC), Aptdo. Correos 73, 46100 Burjassot, Spain5

Received 26 December 2005/ Accepted 22 February 2006

A 62-year-old man with amphotericin B-resistant Candida krusei spondylodiscitis, following an episode of candidemia caused by the same strain, was successfully treated with caspofungin plus voriconazole. Amphotericin B fungicidal concentrations were better predictors of the clinical outcome than were MICs. This is the first case of C. krusei spondylodiscitis reported in the literature.


* Corresponding author. Mailing address: Servicio de Microbiología, Hospital Universitario La Fe, Av. Campanar, 21, 46009 Valencia, Spain. Phone: 34 96 1973333. Fax: 34 96 1973177. E-mail: peman_jav{at}gva.es.


Journal of Clinical Microbiology, May 2006, p. 1912-1914, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1912-1914.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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