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Journal of Clinical Microbiology, May 2006, p. 1917-1918, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1917-1918.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Listeriosis Due to Infection with a Catalase-Negative Strain of Listeria monocytogenes

J. A. Cepeda,1 M. Millar,1 E. A. Sheridan,1 S. Warwick,1 M. Raftery,2 D. C. Bean,3 and D. W. Wareham1,3*

Department of Medical Microbiology, Barts and The London NHS Trust, London, United Kingdom,1 Department of Renal Medicine, Barts and The London NHS Trust, London, United Kingdom,2 Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and The London, Queen Mary's School of Medicine and Dentistry, London, United Kingdom3

Received 12 December 2005/ Returned for modification 28 January 2006/ Accepted 11 February 2006

A strain of Listeria monocytogenes recovered from blood and cerebrospinal fluid had no detectable catalase activity, a characteristic used for primary identification. The sporadic occurrence of pathogenic catalase-negative strains highlights the need for a reconsideration of diagnostic criteria and questions the role of catalase in the pathogenesis of listeria infection.

* Corresponding author. Mailing address: Centre for Infectious Disease, Institute of Cell and Molecular Science, Blizard Building, 4 Newark Street, Whitechapel, London E1 2AT, United Kingdom. Phone: 44 0207 7882 2317. Fax: 44 0207 7882 2181. E-mail: d.w.wareham{at}qmul.ac.uk.

Journal of Clinical Microbiology, May 2006, p. 1917-1918, Vol. 44, No. 5
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.5.1917-1918.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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