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Journal of Clinical Microbiology, June 2006, p. 2158-2159, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.02358-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Detection of Carcinogenic Human Papillomavirus in Specimens Collected with a Novel Self-Sampling Device

Philip E. Castle,1* Asma Aftab,2 Gilbert Saint-Jean,3 and Luis Mendez4

Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, and Departments of,1 Family Medicine and Community Health,2 Epidemiology and Public Health,3 Obstetrics and Gynecology, University of Miami School of Medicine, Miami, Florida4

Received 10 November 2005/ Returned for modification 9 January 2006/ Accepted 10 April 2006

We compared the detection of carcinogenic human papillomavirus DNA in cervicovaginal specimens self-collected using a novel device to the detection in physician-collected cervical specimens from 137 women. The kappa value was 0.66 (95% confidence interval, 0.53 to 0.78), with an 83% overall test agreement and a 68% positive test agreement.

* Corresponding author. Mailing address: Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Room 7074, EPS MSC 7234, Bethesda, MD 20892-7234. Phone: (301) 435-3976. Fax: (301) 402-0916. E-mail: castlep{at}mail.nih.gov.

Journal of Clinical Microbiology, June 2006, p. 2158-2159, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.02358-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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