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Journal of Clinical Microbiology, June 2006, p. 2247-2249, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.00330-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Enterobacterial Autoinducer of Growth Enhances Shiga Toxin Production by Enterohemorrhagic Escherichia coli

W. Voigt,1 A. Fruth,1 H. Tschäpe,1 R. Reissbrodt,1 and P. H. Williams2*

Robert Koch Institut, Wernigerode, Germany,1 Department of Genetics, University of Leicester, Leicester, United Kingdom2

Received 21 February 2005/ Returned for modification 4 April 2005/ Accepted 25 March 2006

The addition of the enterobacterial autoinducer of growth to nutrient-poor minimal medium markedly accelerated the exponential growth rates of strains of enterohemorrhagic Escherichia coli but had little or no effect on maximal cell densities in stationary phase. Growth in the presence of the autoinducer resulted in an approximately twofold enhancement in Shiga toxin production.

* Corresponding author. Mailing address: Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, United Kingdom. Phone: 44 116 252 3317. Fax: 44 116 252 3378. E-mail: phw2{at}le.ac.uk.

Journal of Clinical Microbiology, June 2006, p. 2247-2249, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.00330-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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