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Journal of Clinical Microbiology, June 2006, p. 2271-2275, Vol. 44, No. 6
0095-1137/06/$08.00+0 doi:10.1128/JCM.01890-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Programa de Microbiología, Instituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago, Chile,1 Servicio de Salud Metropolitano del Ambiente (SESMA), Ministerio de Salud de Chile, Santiago, Chile,2 Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio,3 Center for Pediatric Research, Eastern Virginia Medical School and Children's Hospital of The King's Daughters, Norfolk, Virginia4
Received 9 September 2005/ Returned for modification 18 October 2005/ Accepted 8 February 2006
Capsid and polymerase (RdRp) genes of 13 norovirus outbreak strains from Chile were compared. The genes sequences were discordant for five strains, and recombination was confirmed for two of them by amplification of a 1,360-bp gene segment containing a fragment of both genes. These strains belonged to a novel genogroup by RdRp sequence and to genogroup GII/3 by capsid sequence. Determining the clinical and epidemiological impact of human calicivirus recombination will require future studies.
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