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Journal of Clinical Microbiology, June 2006, p. 2307-2310, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.02687-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Diagnosis of Mixed Plasmodium malariae and P. vivax Infection in a Development Aid Volunteer by Examination of Bone-Marrow Specimens by Real-Time PCR

Can Imirzalioglu,1 Nedim Soydan,2 Markus Schaller,2 Reinhard G. Bretzel,2 Trinad Chakraborty,1 and Eugen Domann1*

Center for Tropical Diseases and Travel Medicine, Hospital of the Justus-Liebig University Giessen, Institute of Medical Microbiology, Frankfurter Strasse 107,1 Third Medical Department, Rodthohl 6, D-35392 Giessen, Germany2

Received 27 December 2005/ Returned for modification 11 March 2006/ Accepted 29 March 2006

Mixed Plasmodium malariae and P. vivax infections in humans are reported very infrequently. The case of a 27-year-old male who sustained malaria quartana/tertiana caused by an unbalanced mixed P. malariae-P. vivax infection is reported here. Conventional tests and serology for malarial parasites were uniformly negative. Identification and quantification of the parasites were accomplished by examining bone-marrow specimens using specific real-time TaqMan PCR.

* Corresponding author. Mailing address: Institute of Medical Microbiology, Hospital of the Justus-Liebig University Giessen, Frankfurter Strasse 107, D-35392 Giessen, Germany. Phone: 49-641-9941287. Fax: 49-641-9941259. E-mail: eugen.domann{at}mikrobio.med.uni-giessen.de.

Journal of Clinical Microbiology, June 2006, p. 2307-2310, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.02687-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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