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Journal of Clinical Microbiology, July 2006, p. 2609-2611, Vol. 44, No. 7
0095-1137/06/$08.00+0 doi:10.1128/JCM.00572-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Department of Pathology,1 Division of Infectious Diseases, Hackensack University Medical Center, Hackensack, New Jersey,2 University of Medicine and Dentistry of New Jersey, Newark, New Jersey3
Received 16 March 2006/ Returned for modification 12 April 2006/ Accepted 18 April 2006
We applied 16S rRNA gene sequencing to identify bacterial species present in formalin-fixed, paraffin-embedded heart valve tissue. In 40% (12/30) of the cases, we were able to identify the bacterium to the species-genus level. For more recent cases (
4 years), the success rate was significantly improved, to 70% (P < 0.001).
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