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Journal of Clinical Microbiology, July 2006, p. 2635-2637, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.00509-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Sequence Analysis of Enterococcus faecium Strain 10/96A (VanD4), the Original Vancomycin-Resistant E. faecium Strain in Brazil

Ilana L. B. C. Camargo,1 Libera M. Dalla Costa,2 Neil Woodford,3 Michael S. Gilmore,4 and Ana L. C. Darini1*

Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de São Paulo, Ribeirão Preto, Brazil,1 Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, Brazil,2 Antibiotic Resistance Monitoring and Reference Laboratory, Centre for Infections, Health Protection Agency, London NW9 5EQ, United Kingdom,3 Schepens Eye Research Institute, Harvard Medical School, 20 Staniford Street, Boston, Massachusetts 021144

Received 8 March 2006/ Returned for modification 9 April 2006/ Accepted 30 April 2006

Enterococcus faecium strain 10/96A (VanD4) was the first vancomycin-resistant enterococcus (VRE) isolated in Brazil. Subsequent Brazilian VRE strains have all had the VanA phenotype. Multilocus sequence typing showed that strain 10/96A was isolated sporadically, has a unique sequence type (ST 281), and was not the progenitor of the VRE strains isolated from hospital outbreaks in Brazil.

* Corresponding author. Mailing address: Av do Cafe s/n, Monte Alegre, Ribeirao Preto, São Paulo, Brazil 14040-903. Phone: 55 16 602 429. Fax: 55 16 633 1936. E-mail: aldarini{at}fcfrp.usp.br.

Journal of Clinical Microbiology, July 2006, p. 2635-2637, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.00509-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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