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Journal of Clinical Microbiology, July 2006, p. 2638-2641, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.02644-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Evaluation of the Quidel QuickVue Test for Detection of Influenza A and B Viruses in the Pediatric Emergency Medicine Setting by Use of Three Specimen Collection Methods

Konstantinos Agoritsas,3 Kathy Mack,4 Bema K. Bonsu,2,3 Debbie Goodman,3 Douglas Salamon,4 and Mario J. Marcon1,4*

Departments of Pathology,1 Pediatrics, The Ohio State University College of Medicine and Public Health,2 Departments of Emergency Medicine,3 Laboratory Medicine, Children's Hospital, Columbus, Ohio 432054

Received 21 December 2005/ Returned for modification 20 February 2006/ Accepted 23 April 2006

The Quidel QuickVue influenza test was compared to viral culture and reverse transcriptase PCR by the use of three different respiratory specimen types. Of 122 pediatric subjects enrolled, 59 had influenza virus infections: 44 were infected with influenza A virus and 15 were infected with influenza B virus. The sensitivity of the QuickVue test was 85% with nasopharyngeal swabs, 78% with nasal swabs, and 69% with nasopharyngeal washes. Specificities were equivalent (97% to 98%) for all three collection methods.

* Corresponding author. Mailing address: Department of Laboratory Medicine, Rm. C1868, Columbus Children's Hospital, 700 Children's Drive, Columbus, OH 43205. Phone: (614) 722-5383. Fax: (614) 722-5308. E-mail: marconm{at}chi.osu.edu.

Journal of Clinical Microbiology, July 2006, p. 2638-2641, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.02644-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2006 by the American Society for Microbiology. All rights reserved.