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Journal of Clinical Microbiology, August 2006, p. 3005-3007, Vol. 44, No. 8
0095-1137/06/$08.00+0     doi:10.1128/JCM.00552-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Use of an Immunochromatographic Dipstick Test for Rapid Detection of Trypanosoma cruzi in Sera from Animal Reservoir Hosts

Marta V. Cardinal,1 Richard Reithinger,2* and Ricardo E. Gürtler1

Department of Ecology, Genetics and Evolution, Universidad de Buenos Aires, Buenos Aires, Argentina,1 Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London WC1E 7HT, United Kingdom2

Received 14 March 2006/ Returned for modification 13 April 2006/ Accepted 9 May 2006

We evaluated an immunochromatographic dipstick test to detect Trypanosoma cruzi in canine serum samples from areas of endemicity (n = 141) and nonendemicity (n = 28) for Chagas' disease with known serological and xenodiagnostic test results. The dipstick test had a specificity of at least 94% and a sensitivity of at least 96%. The dipstick tested could become the first choice for screening purposes in disease surveillance or intervention programs.

* Corresponding author. Mailing address: 807 S. Overlook Drive, Alexandria, VA 22305. Phone: (703) 838-2852. E-mail: rreithinger{at}yahoo.co.uk.

Journal of Clinical Microbiology, August 2006, p. 3005-3007, Vol. 44, No. 8
0095-1137/06/$08.00+0     doi:10.1128/JCM.00552-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Houghton, R. L., Stevens, Y. Y., Hjerrild, K., Guderian, J., Okamoto, M., Kabir, M., Reed, S. G., Leiby, D. A., Morrow, W. J. W., Lorca, M., Raychaudhuri, S. (2009). Lateral Flow Immunoassay for Diagnosis of Trypanosoma cruzi Infection with High Correlation to the Radioimmunoprecipitation Assay. CVI 16: 515-520 [Abstract] [Full Text]  


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