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Journal of Clinical Microbiology, September 2006, p. 3368-3370, Vol. 44, No. 9
0095-1137/06/$08.00+0     doi:10.1128/JCM.00850-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Nosocomial Spread of Enterococcus faecium Resistant to Vancomycin and Linezolid in a Tertiary Care Medical Center

Thomas E. Dobbs,1 Mukesh Patel,1 Ken B. Waites,2* Stephen A. Moser,2 Alan M. Stamm,1 and Craig J. Hoesley1

Department of Medicine,1 Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249-73312

Received 21 April 2006/ Accepted 26 June 2006

In May 2004 our institution encountered its first clinical isolate of linezolid-resistant, vancomycin-resistant Enterococcus faecium (LRVRE). Between October 2004 and July 2005, 40 patients from whom LRVRE organisms were recovered in clinical specimens were characterized. Epidemiologic investigation and pulsed-field gel electrophoresis patterns indicated a clonal outbreak related to nosocomial spread.

* Corresponding author. Mailing address: University of Alabama at Birmingham, 619 South 19th St., Birmingham, AL 35249. Phone: (205) 934-4960. Fax: (205) 975-4468. E-mail: waites{at}path.uab.edu.

Journal of Clinical Microbiology, September 2006, p. 3368-3370, Vol. 44, No. 9
0095-1137/06/$08.00+0     doi:10.1128/JCM.00850-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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