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Journal of Clinical Microbiology, January 2007, p. 246-247, Vol. 45, No. 1
0095-1137/07/$08.00+0     doi:10.1128/JCM.01403-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Comparison of Serological Test Kits for Diagnosis of Typhoid Fever in the Philippines{triangledown}

Razel L. Kawano,* Susan A. Leano, and Dorothy May A. Agdamag

National Reference Laboratory for HIV/AIDS, Hepatitis, and other STDs, STD/AIDS Cooperative Central Laboratory, Manila, Philippines

Received 7 July 2006/ Returned for modification 21 August 2006/ Accepted 18 October 2006

We evaluated four recent antibody-detection kits for typhoid fever by using 177 febrile patients from our hospital, in 75 of whom Salmonella enterica serotype Typhi grew. TUBEX performed best, achieving 94.7% sensitivity and 80.4% specificity. Typhidot, SD Bioline Typhoid, and Mega Salmonella were less specific and, in most cases, less sensitive.

* Corresponding author. Mailing address: National Reference Laboratory for HIV/AIDS, Hepatitis and Other STDs, STD/AIDS Cooperative Central Laboratory, Manila, Philippines. Phone and fax: 632-309-9528. E-mail: rzlkawano{at}yahoo.com.

{triangledown} Published ahead of print on 25 October 2006.

Journal of Clinical Microbiology, January 2007, p. 246-247, Vol. 45, No. 1
0095-1137/07/$08.00+0     doi:10.1128/JCM.01403-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Tam, F. C. H., Leung, D. T. M., Ma, C. H., Lim, P.-L. (2008). Modification of the TUBEX typhoid test to detect antibodies directly from haemolytic serum and whole blood. J Med Microbiol 57: 1349-1353 [Abstract] [Full Text]  
  • Tam, F. C. H., Ling, T. K. W., Wong, K. T., Leung, D. T. M., Chan, R. C. Y., Lim, P. L. (2008). The TUBEX test detects not only typhoid-specific antibodies but also soluble antigens and whole bacteria. J Med Microbiol 57: 316-323 [Abstract] [Full Text]  


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