This Article Full Text Full Text (PDF) Other Versions of this Article: JCM.01125-07v1 45/11/3771    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Gilmour, M. W. Articles by Ng, L.-K. Search for Related Content PubMed PubMed Citation Articles by Gilmour, M. W. Articles by Ng, L.-K.

Isolation and Genetic Characterization of a Coinfection of Non-O157 Shiga Toxin-Producing Escherichia coli

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba,¹ Laboratory for Food Zoonoses, Public Health Agency of Canada, Guelph, Ontario,² IWK Health Center, Dalhousie University, Halifax, Nova Scotia, Canada³

Received 5 June 2007/ Returned for modification 19 July 2007/ Accepted 14 August 2007

A coinfection of O177:NM and O55:H7 Shiga toxin-producing Escherichia coli (STEC) was identified for a child with acute bloody diarrhea and hemolytic uremic syndrome by using culture and serotype-specific molecular reagents. The profile of O157-related genetic islands revealed that the O55:H7 isolate was highly similar to O157 STEC whereas the O177:NM isolate lacked several fimbrial O islands and non-locus-of-enterocyte-effacement effector determinants. However, both STEC serotypes are known to cause serious disease, and the significant repertoire of virulence determinants in both strains made it impossible to determine their individual contributions to the clinical symptoms.

Published ahead of print on 5 September 2007.