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Journal of Clinical Microbiology, November 2007, p. 3771-3773, Vol. 45, No. 11
0095-1137/07/$08.00+0     doi:10.1128/JCM.01125-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Isolation and Genetic Characterization of a Coinfection of Non-O157 Shiga Toxin-Producing Escherichia coli{triangledown}

Matthew W. Gilmour,1 Helen Tabor,1 Gehua Wang,1 Clifford G. Clark,1 Dobryan M. Tracz,1 Adam B. Olson,1 Mariola Mascarenhas,2 Mohamed A. Karmali,2 Tim Mailman,3 and Lai-King Ng1*

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba,1 Laboratory for Food Zoonoses, Public Health Agency of Canada, Guelph, Ontario,2 IWK Health Center, Dalhousie University, Halifax, Nova Scotia, Canada3

Received 5 June 2007/ Returned for modification 19 July 2007/ Accepted 14 August 2007

A coinfection of O177:NM and O55:H7 Shiga toxin-producing Escherichia coli (STEC) was identified for a child with acute bloody diarrhea and hemolytic uremic syndrome by using culture and serotype-specific molecular reagents. The profile of O157-related genetic islands revealed that the O55:H7 isolate was highly similar to O157 STEC whereas the O177:NM isolate lacked several fimbrial O islands and non-locus-of-enterocyte-effacement effector determinants. However, both STEC serotypes are known to cause serious disease, and the significant repertoire of virulence determinants in both strains made it impossible to determine their individual contributions to the clinical symptoms.

* Corresponding author. Mailing address: National Microbiology Laboratory, 1015 Arlington Street, Winnipeg, Manitoba, Canada R3E 3R2. Phone: (204) 789-2131. Fax: (204) 789-5012. E-mail: Lai_King_Ng{at}phac-aspc.gc.ca

{triangledown} Published ahead of print on 5 September 2007.

Journal of Clinical Microbiology, November 2007, p. 3771-3773, Vol. 45, No. 11
0095-1137/07/$08.00+0     doi:10.1128/JCM.01125-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

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