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Journal of Clinical Microbiology, November 2007, p. 3824-3827, Vol. 45, No. 11
0095-1137/07/$08.00+0     doi:10.1128/JCM.01288-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

First Detection of G12 Rotaviruses in Newborns with Neonatal Rotavirus Infection at All India Institute of Medical Sciences, New Delhi, India{triangledown}

Pratima Ray,1* S. Sharma,1 R. K. Agarwal,2 K. Longmei,1 J. R. Gentsch,3 V. K. Paul,2 R. I. Glass,4 and M. K. Bhan1

Center for Diarrheal Disease Research,1 Neonatal Unit, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India,2 Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia,3 Fogarty International Center, National Institutes of Health, Bethesda, Maryland4

Received 26 June 2007/ Returned for modification 2 August 2007/ Accepted 19 August 2007

Rotavirus genotype G12 strains were detected for the first time among newborns with asymptomatic rotavirus infection (74% of 39 rotavirus strains isolated from the infected infants were genotype G12) in the nursery of the All India Institute of Medical Sciences during a period from 2005 to 2006. Sequence analysis of the VP7 genes from these neonatal strains indicated a high level of homology to other G12 strains reported worldwide, suggesting the recent emergence of these strains in humans. Such nosocomial infections of newborns represent a potential source of introduction of novel rotavirus serotypes into the community.

* Corresponding author. Mailing address: Center for Diarrheal Disease Research, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India. Phone: 26589809. Fax: 91-11-26586663. E-mail: pratimaray{at}gmail.com

{triangledown} Published ahead of print on 29 August 2007.

Journal of Clinical Microbiology, November 2007, p. 3824-3827, Vol. 45, No. 11
0095-1137/07/$08.00+0     doi:10.1128/JCM.01288-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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