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Journal of Clinical Microbiology, November 2007, p. 3830-3832, Vol. 45, No. 11
0095-1137/07/$08.00+0     doi:10.1128/JCM.01297-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Simultaneous Infection with More than One Strain of Burkholderia pseudomallei Is Uncommon in Human Melioidosis{triangledown}

Direk Limmathurotsakul,1 Vanaporn Wuthiekanun,1 Narisara Chantratita,1 Gumphol Wongsuvan,1 Aunchalee Thanwisai,1 Mayurachat Biaklang,1 Sarinna Tumapa,1 Sue Lee,1 Nicholas P. J. Day,1,2 and Sharon J. Peacock1,2*

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand,1 Center for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom2

Received 27 June 2007/ Returned for modification 16 August 2007/ Accepted 27 August 2007

A prospective study was performed to determine the rate at which patients with melioidosis are infected with more than one strain of Burkholderia pseudomallei. Genotyping of 2,058 bacterial colonies isolated from 215 samples taken from 133 patients demonstrated that mixed infection is uncommon (2/133 cases [1.5%; 95% confidence interval, 0.2 to 5.3%]).

* Corresponding author. Mailing address: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand. Phone: 66 2 354 9172. Fax: 66 2 354 9169. E-mail: sharon{at}tropmedres.ac

{triangledown} Published ahead of print on 5 September 2007.

Journal of Clinical Microbiology, November 2007, p. 3830-3832, Vol. 45, No. 11
0095-1137/07/$08.00+0     doi:10.1128/JCM.01297-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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Copyright © 2007 by the American Society for Microbiology. All rights reserved.