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Journal of Clinical Microbiology, February 2007, p. 568-571, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.01684-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Discovering Potential Pathogens among Fungi Identified as Nonsporulating Molds{triangledown}

June I. Pounder,1* Keith E. Simmon,1 Claudia A. Barton,2 Sheri L. Hohmann,2 Mary E. Brandt,3 and Cathy A. Petti1,2,4

Associated Regional and University Pathologists, Inc., Institute for Clinical and Experimental Pathology, Salt Lake City, Utah,1 Associated Regional and University Pathologists, Inc., Infectious Diseases Laboratory, Salt Lake City, Utah,2 Centers for Disease Control and Prevention, Mycotic Disease Branch, Atlanta, Georgia,3 University of Utah School of Medicine, Salt Lake City, Utah4

Received 15 August 2006/ Returned for modification 12 October 2006/ Accepted 15 November 2006

Fungal infections are increasing, particularly among immunocompromised hosts, and a rapid diagnosis is essential to initiate antifungal therapy. Often fungi cannot be identified by conventional methods and are classified as nonsporulating molds (NSM).We sequenced internal transcribed spacer regions from 50 cultures of NSM and found 16 potential pathogens that can be associated with clinical disease. In selected clinical settings, identification of NSM could prove valuable and have an immediate impact on patient management.

* Corresponding author. Mailing address: ARUP Laboratories, 500 Chipeta Way, Salt Lake City, UT 84108. Phone: (801) 583-2787, ext. 3223. Fax: (801) 584-5109. E-mail: june.pounder{at}aruplab.com.

{triangledown} Published ahead of print on 29 November 2006.

Journal of Clinical Microbiology, February 2007, p. 568-571, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.01684-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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