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Journal of Clinical Microbiology, February 2007, p. 648-650, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.01151-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Molecular Confirmation that Fasciola gigantica Can Undertake Aberrant Migrations in Human Hosts{triangledown}

Thanh Hoa Le,1 Nguyen Van De,2 Takeshi Agatsuma,3 David Blair,4* Jozef Vercruysse,5 Pierre Dorny,5 Thanh Giang Thi Nguyen,1 and Donald P. McManus6

Department of Immunology, Institute of Biotechnology, Hanoi, Vietnam,1 Faculty of Parasitology, Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam,2 Department of Environmental Health Sciences, Kochi Medical School, Kochi, Japan,3 School of Tropical Biology, James Cook University, Townsville, QLD 4811, Australia,4 Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium,5 Queensland Institute of Medical Research, Brisbane, QLD 4006, Australia6

Received 5 June 2006/ Returned for modification 6 July 2006/ Accepted 9 October 2006

Two cases of aberrant migration by the liver fluke Fasciola gigantica in humans are reported. In both cases, subadult worms emerged through the skin. The identity of the worms was confirmed from their DNA sequences. This uncommon human pathogen might be more likely than F. hepatica to undertake aberrant migrations in humans.

* Corresponding author. Mailing address: School of Tropical Biology, James Cook University, Townsville, QLD 4811, Australia. Phone: 61 7 4781 4322. Fax: 61 7 4725 1570. E-mail: david.blair{at}jcu.edu.au.

{triangledown} Published ahead of print on 29 November 2006.

Journal of Clinical Microbiology, February 2007, p. 648-650, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.01151-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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