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Journal of Clinical Microbiology, February 2007, p. 662-665, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.02058-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Burkholderia glumae Infection in an Infant with Chronic Granulomatous Disease{triangledown}

Jason B. Weinberg,1 Barbara D. Alexander,2 Joseph M. Majure,2 Larry W. Williams,2 Jason Y. Kim,3 Peter Vandamme,4 and John J. LiPuma1*

Division of Infectious Diseases, Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan,1 Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Durham, North Carolina,2 Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania,3 Laboratorium voor Microbiologie, Universiteit Gent, K. L. Ledeganckstraat 35, B-9000 Gent, Belgium4

Received 5 October 2006/ Accepted 13 November 2006

An 8-month-old boy developed a necrotic lung mass from which Burkholderia glumae was recovered, leading to the diagnosis of chronic granulomatous disease (CGD). While other Burkholderia species have been identified as important pathogens in persons with CGD, B. glumae has not been previously reported to cause human infection.

* Corresponding author. Mailing address: 8323 MSRB III, Box 0646, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-0646. Phone: (734) 936-9767. Fax: (734) 764-4279. E-mail: jlipuma{at}umich.edu.

{triangledown} Published ahead of print on 29 November 2006.

Journal of Clinical Microbiology, February 2007, p. 662-665, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.02058-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Devescovi, G., Bigirimana, J., Degrassi, G., Cabrio, L., LiPuma, J. J., Kim, J., Hwang, I., Venturi, V. (2007). Involvement of a Quorum-Sensing-Regulated Lipase Secreted by a Clinical Isolate of Burkholderia glumae in Severe Disease Symptoms in Rice. Appl. Environ. Microbiol. 73: 4950-4958 [Abstract] [Full Text]  


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