Journal of Clinical Microbiology, March 2007, p. 1016-1018, Vol. 45, No. 3
0095-1137/07/$08.00+0 doi:10.1128/JCM.02085-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Cultivation-Independent Analysis of Changes in Bacterial Vaginosis Flora Following Metronidazole Treatment
Michael J. Ferris,1,2*
Johana Norori,2
Marcela Zozaya-Hinchliffe,2 and
David H. Martin3
Department of Pediatrics,1
Department of Internal Medicine, Louisiana State University Health Sciences Center, New, Orleans, Louisiana 70112,3
The Research Institute for Children, New Orleans, Louisiana 701182
Received 10 October 2006/
Returned for modification 20 November 2006/
Accepted 19 December 2006
PCR was used to survey bacterial vaginosis flora before and after metronidazole treatment. The species composition for pretreatment patients was variable. Lactobacillus iners was prominent in all patients posttreatment. Atopobium vaginae concentrations were highest for patients who failed or responded incompletely to treatment and lowest for patients who were cured.
* Corresponding author. Mailing address: Children's Hospital, R&E Bldg., 200 Henry Clay Ave., New Orleans, LA 70118. Phone: (504) 896-2736. Fax: (504) 894-5379. E-mail: mferris{at}chnola-research.org.
Published ahead of print on 3 January 2007.
Journal of Clinical Microbiology, March 2007, p. 1016-1018, Vol. 45, No. 3
0095-1137/07/$08.00+0 doi:10.1128/JCM.02085-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
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Copyright © 2007 by the American Society for Microbiology. All rights reserved.